Rekord LOINC: 53711-8

Dostępne tłumaczenie polskie ACTIVE

Tłumaczenie polskie
Komponent
Właściwość
Aspekt czasowy
System
Typ skali
Klasa
Krótka nazwa
Długa nazwa wspólna
Definicja i opis
Szczegóły rekordu LOINC
Informacje podstawowe
Kod LOINC: 53711-8 FHIR
Long Common Name: Neuronal nuclear type 1 Ab [Titer] in Cerebral spinal fluid
Short Name: Hu1 Ab Titr CSF
Status: ACTIVE
Class Type: 1
Fully Specified Name (FSN)
PL Tłumaczenie polskie
Typ 1 neuronalny jądrowy Ab : miano : punkt w czasie : płyn mózgowo-rdzeniowy : półilościowy : -
EN Oryginalna wersja angielska
Neuronal nuclear type 1 Ab : Titr : Pt : CSF : SemiQn : -
Klasyfikacja
Class:
PLserologia niemikrobiologiczna
ENSERO
Consumer Name: -
Order/Observation: Both
Panel Type: -
Informacje dodatkowe
Units Required: N
Example Units: titer
UCUM Units: {titer}
Version Last Changed: 2.75
Definicja i opis
EN Anti-Neuronal Nuclear Antibody Type 1 Cerebrospinal fluid (CSF) titer. This antibody recognizes a 35-40 kD component found in neuronal cell nuclei. ANNA-1 antibody is found almost exclusively in patients with a history of tobacco use or passive exposure. Women are affected twice as often as men. Cancer has been found in more than 90% of seropositive patients. Small cell lung carcinoma (SCLC) has been found in 80% of patients. A second malignant neoplasm is found in 13% of patients positive for ANNA-1 who have SCLC. The most common clinical presentation of patients positive for ANNA-1 is peripheral neuropathy, but they can exhibit any element of encephalomyeloradiculopathy. About 10% of patients present with gastroparesis or intestinal obstruction. ANNA-1 has also been detected in children with intestinal dysmotility, cerbellar ataxia, and brainstem encephalitis with and without neuroblastoma. It is detected in 5 to 10% of patients with SCLC who do not have a paraneoplastic syndrome. Paraneoplastic syndromes are autoantibody-mediated neurologic disorders associated with underlying tumors. These syndromes arise when systemic tumors express antigens normally found only in neural tissue. Serum is the preferred specimen. CSF results are sometimes positive when serum results are negative. If a lumbar puncture is going to be performed as part of the diagnostic workup, CSF testing is recommended to improve the detection rate. Information from http://www.clinlabnavigator.com accessed 2008 15 02.
Powiązane nazwy

Przeciwciała do antygenów jądrowych neuronów typu 1 Przeciwciała onkoneuronalne