Rekord LOINC: 70278-7
Tylko wersja angielska ACTIVE
Szczegóły rekordu LOINC
Informacje podstawowe
| Kod LOINC: |
70278-7
FHIR
|
| Long Common Name: | t(3;21)(q26;q22.3)(MECOM,RUNX1) fusion transcript [Presence] in Blood or Tissue by Molecular genetics method |
| Short Name: | t(3;21)(MECOM,RUNX1) Bld/T Ql |
| Status: | ACTIVE |
| Class Type: | 1 |
Fully Specified Name (FSN)
EN
Oryginalna wersja angielska
t(3;21)(q26;q22.3)(MECOM,RUNX1) fusion transcript
:
Arb
:
Pt
:
Bld/Tiss
:
Ord
:
Molgen
Klasyfikacja
| Class: |
ENMOLPATH.TRNLOC
|
| Consumer Name: | - |
| Order/Observation: | Both |
| Panel Type: | - |
Informacje dodatkowe
| Units Required: | N |
| Example Units: | - |
| UCUM Units: | - |
| Version Last Changed: | 2.40 |
Definicja i opis
EN
This term is used to identify a leukemia causing chromosomal translocation resulting in a gene fusion between MECOM (3q26) and RUNX1 (21q22) genes. The term was created for (but not limited to) DNA Technology's HemaVision HV01-28N kit, a qualitative in vitro diagnostic test for 28 leukemia causing chromosomal alterations including more than 80 breakpoints plus associated mRNA splice variants. Reverse transcription followed by multiplex nested polymerase chain reactions (RT-PCR) and agarose gel electrophoresis are used to identify gene fusions caused by chromosomal translocations, gene deletions or inversions. Testing information is useful for predicting development of the disease and selection of treatment.
Powiązane nazwy
21q22.3; Acute myeloid leukemia 1; AML1; Arbitrary; Blood; CBFA2; DNA; gene fusion; gene translocation; Genetics; Heredity; Heritable; III; Inherited; Molecular genetics; Molecular pathology; MOLPATH; MOLPATH.TRANSLOCATION; Ordinal; PCR; Point in time; QL; Qual; Qualitative; Random; RNA; Screen; T prime; t(3;21)(MECOM,RUNX1); Tissue; Tissue, unspecified; translocation; WB; Whole blood; Whole blood or Tissue