Rekord LOINC: 74676-8
Dostępne tłumaczenie polskie ACTIVE
Tłumaczenie polskie
Komponent
Właściwość
Aspekt czasowy
System
Typ skali
Typ metody
Klasa
Krótka nazwa
Długa nazwa wspólna
Definicja i opis
Szczegóły rekordu LOINC
Informacje podstawowe
| Kod LOINC: |
74676-8
FHIR
|
| Long Common Name: | Carbapenemase [Type] in Isolate by Carba NP |
| Short Name: | Carbapenemase Islt |
| Status: | ACTIVE |
| Class Type: | 1 |
Fully Specified Name (FSN)
PL
Tłumaczenie polskie
Karbapenemaza
:
typ
:
punkt w czasie
:
izolat
:
skala nominalna
:
karbapenemaza Nordmanna i Porela
EN
Oryginalna wersja angielska
Carbapenemase
:
Type
:
Pt
:
Isolate
:
Nom
:
Carbapenemase Nordmann-Poirel
Klasyfikacja
| Class: |
PLMICRO
ENMICRO
|
| Consumer Name: | - |
| Order/Observation: | Both |
| Panel Type: | - |
Informacje dodatkowe
| Units Required: | - |
| Example Units: | - |
| UCUM Units: | - |
| Version Last Changed: | 2.73 |
Definicja i opis
EN
The Carba NP (Carbapenemase Nordmann-Poirel) test rapidly (<2 hrs) detects carbapenemase production in isolates of Enterobacteriaceae and Pseudomonas aeruginosa. Carbapenemases are detected and can be differentiated by the CarbaNP test when the test isolate produces the enzyme (in the absence of a chemical inhibitor) that hydrolyzes imipenem (a carbapenem antibiotic) into the carboxylic form of the antibiotic, thereby lowering the pH of the reaction solution which contains phenol red indicator. The acidification changes the red color of the reaction solution to orange-yellow color (positive result) that can be visualized easily with the naked eye. Carba NP testing can detect the following carbapenemase types: Klebsiella pneumoniae carbapenemase (KPC; Ambler class A); Verona integron-encoded metallo-β-lactamase (VIM), imipenemase (IMP), New Delhi metallo-β-lactamase (NDM) (all Ambler class B); and oxacillinase-48 (OXA-48; Ambler class D). For this test, each test isolate is inoculated into 4 reaction wells or tubes: one without any antibiotic or chemical inhibitor against carbapenemases, one containing imipenem without any chemical inhibitor, one containing impenem and tazobactam (which inhibits KPC carbapenemases), one containing imipenem and EDTA (which inhibits VIM, IMP, and NDM carbapenemases). Based on the presence and absence of color change among the 4 reaction wells or tubes, one can differentiate among the 3 classes of carbapenemases. However, differentiation is not possible with this test in isolates that produce more than one class of carbapenemases simultaneously.
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